Caenorhabditis elegansGenAge entry for miro-1 (Caenorhabditis elegans)

Gene information (ID: 2095)

Symbol
miro-1
Name
Mitochondrial Rho GTPase 1
Organism
Caenorhabditis elegans (AnAge)

Potential relevance to longevity and/or ageing

Observations
Downregulation of miro-1 simultaneously in multiple tissues resulted in an increase in lifespan. In addition the amount of mitochondria in miro-1 mutants was approximately 50% of the wild type.
% change in avg or median lifespan
Median lifespan is 50% higher.
Lifespan Effect
Increase
Genetic Manipulation
RNA interference
Longevity Category
Anti-Longevity
Primary reference

    Homologs in other organisms

    Danio rerio
    rhot2
    Drosophila melanogaster
    Miro
    Homo sapiens
    RHOT2
    Mus musculus
    Rhot2
    Rattus norvegicus
    Rhot2

    External links

    WormBase
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    Ensembl
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    Entrez Gene
    View on Entrez Gene database (177238)
    Homologues
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    UniProt
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    Internet
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