GenAge entry for mir-277 (Drosophila melanogaster)
Gene information (ID: 2170)
- mir-277 stem loop
- Drosophila melanogaster (AnAge)
Potential relevance to longevity and/or ageing
- Flies overexpressing miR-277 demonstrated a decrease in lifespan. The decrease in lifespan was consistent between male and female flies and on different dietary regimes. Additionally, flies expressing a mutant form of miR-277 demonstrated a significantly longer lifespan than wild type flies and flies overexpressing miR-277 (70%).
- % change in avg or median lifespan
- Median lifespan is 70% higher.
- Lifespan Effect
- Genetic Manipulation
- Longevity Category
- Primary reference
Homologs in other organisms
No homologs found