Caenorhabditis elegansGenAge entry for lipl-4 (Caenorhabditis elegans)

Gene information (ID: 1881)

Symbol
lipl-4
Name
LIPase Like
Organism
Caenorhabditis elegans (AnAge)

Potential relevance to longevity and/or ageing

Observations
Constitutive transgenic expression of lipl-4 in the intestine results in a 55% mean lifespan increase compared to wild-type.
% change in max lifespan
Maximum lifespan is aproximately 25% higher.
% change in avg or median lifespan
Mean lifespan is 55% higher.
Lifespan Effect
Increase
Genetic Manipulation
Overexpression
Longevity Category
Pro-Longevity
Primary reference
    Observations
    Constitutive expression of lipl-4 (K04A8.5) in the intestine extends worm mean lifespan by 24%.
    % change in avg or median lifespan
    Mean lifespan is 24% higher.
    Lifespan Effect
    Increase
    Genetic Manipulation
    Overexpression
    Longevity Category
    Pro-Longevity
    Primary reference

      Homologs in other organisms

      Danio rerio
      lipf
      Homo sapiens
      LIPM
      Mus musculus
      Lipo4
      Rattus norvegicus
      LOC100360690

      External links

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      Entrez Gene
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      Homologues
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      UniProt
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      Internet
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