Caenorhabditis elegansGenAge entry for lin-28 (Caenorhabditis elegans)

Gene information (ID: 2092)

Symbol
lin-28
Name
Protein lin-28
Organism
Caenorhabditis elegans (AnAge)

Potential relevance to longevity and/or ageing

Observations
When C. elegans were fed bacteria containing double-stranded lin-28 RNA from the L1 larval stage they showed a 20.3% increase in lifespan. When fed from the young adult stage they showed an 8.6% increase in lifespan instead.
% change in avg or median lifespan
Mean lifespan is 20% higher.
Lifespan Effect
Increase
Genetic Manipulation
RNA interference
Longevity Category
Anti-Longevity
Primary reference

    Homologs in other organisms

    Danio rerio
    CABZ01076796.1
    Drosophila melanogaster
    lin-28
    Homo sapiens
    LIN28A
    Mus musculus
    Lin28a
    Rattus norvegicus
    Lin28b

    External links

    WormBase
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    Ensembl
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    Entrez Gene
    View on Entrez Gene database (172626)
    Homologues
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    UniProt
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    Internet
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