Caenorhabditis elegansGenAge entry for lgg-1 (Caenorhabditis elegans)

Gene information (ID: 955)

Symbol
lgg-1
Name
LC3, GABARAP and GATE-16 family
Organism
Caenorhabditis elegans (AnAge)

Potential relevance to longevity and/or ageing

Observations
43% mean LS reduction
% change in avg or median lifespan
Average lifespan is 43% lower.
Lifespan Effect
Decrease
Genetic Manipulation
RNA interference
Longevity Category
Pro-Longevity
Primary reference
    Observations
    12% maximal lifespan reduction compared to wild-type by RNAi from the beginning of life. Postdevelopmental RNAi caused a maximum lifespan reduction by 10% compared to wild-type.
    % change in max lifespan
    Maximum lifespan is 10-12% higher.
    Lifespan Effect
    Decrease
    Genetic Manipulation
    RNA interference
    Longevity Category
    Pro-Longevity
    Primary reference

      In other databases

      GenAge model organism genes
      • A homolog of this gene for Drosophila melanogaster is present as Atg8a
      • A homolog of this gene for Saccharomyces cerevisiae is present as ATG8
      GenDR gene manipulations
      • A homolog of this gene for Saccharomyces cerevisiae is present as ATG8

      Homologs in other organisms

      Danio rerio
      gabarapa
      Drosophila melanogaster
      Atg8a
      Homo sapiens
      GABARAPL3
      Mus musculus
      Gabarapl1
      Rattus norvegicus
      Gabarapl1
      Saccharomyces cerevisiae
      ATG8
      Schizosaccharomyces pombe
      atg8

      External links

      WormBase
      Search
      Ensembl
      Search
      Entrez Gene
      View on Entrez Gene database (174050)
      Homologues
      Search HomoloGene
      UniProt
      Search
      Internet
      Search Google or Search Google Scholar