Caenorhabditis elegansGenAge entry for letm-1 (Caenorhabditis elegans)

Gene information (ID: 1940)

Symbol
letm-1
Name
LETM1 (Leucine zipper, EF-hand, TransMembrane mitochondrial protein) homolog
Organism
Caenorhabditis elegans (AnAge)

Potential relevance to longevity and/or ageing

Observations
RNA interference of letm-1 extends mean lifespan (by 21.1%) compared to wild-type worms.
% change in avg or median lifespan
Mean lifespan is 21% higher.
Lifespan Effect
Increase
Genetic Manipulation
RNA interference
Longevity Category
Anti-Longevity
Primary reference

    Homologs in other organisms

    Danio rerio
    letm1
    Drosophila melanogaster
    Letm1
    Homo sapiens
    LETM1
    Mus musculus
    Letm1
    Rattus norvegicus
    Letm1
    Saccharomyces cerevisiae
    YLH47

    External links

    WormBase
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    Ensembl
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    Entrez Gene
    View on Entrez Gene database (179854)
    Homologues
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    UniProt
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    Internet
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