Caenorhabditis elegansGenAge entry for let-418 (Caenorhabditis elegans)

Gene information (ID: 1906)

Symbol
let-418
Name
Protein let-418
Organism
Caenorhabditis elegans (AnAge)

Potential relevance to longevity and/or ageing

Observations
LET-418 worm mutants (loss-of-function mutation) display an increased lifespan and stress resistance to stress in a daf-16-dependent manner.
% change in avg or median lifespan
Lifespan is up to 25% higher.
Lifespan Effect
Increase
Genetic Manipulation
Mutation
Longevity Category
Anti-Longevity
Primary reference

    Homologs in other organisms

    Danio rerio
    chd4a
    Drosophila melanogaster
    Mi-2
    Rattus norvegicus
    Chd3
    Schizosaccharomyces pombe
    mit1

    External links

    WormBase
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    Ensembl
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    Entrez Gene
    View on Entrez Gene database (178970)
    Homologues
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    UniProt
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    Internet
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