Drosophila melanogasterGenAge entry for l(3)neo18 (Drosophila melanogaster)

Gene information (ID: 862)

Symbol
l(3)neo18
Aliases
CG9762; Dmel\CG9762
Name
l(3)neo18
Organism
Drosophila melanogaster (AnAge)

Potential relevance to longevity and/or ageing

Observations
In females, RNAi increased mean life span by 14-18% when done both during development and adulthood in the whole organism and by 8-24% when done in the neurons. In males, the effect is more variable. A consistent increase (8-18%) was however observed for whole organism RNAi, in adults.
% change in avg or median lifespan
Average female lifespan is up to 24% higher.
Lifespan Effect
Increase
Genetic Manipulation
RNA interference
Longevity Category
Anti-Longevity
Primary reference

    In other databases

    GenAge model organism genes
    • A homolog of this gene for Caenorhabditis elegans is present as CELE_C25H3.9
    GenDR gene manipulations

    Homologs in other organisms

    Caenorhabditis elegans
    C25H3.9
    Danio rerio
    ndufb5
    Homo sapiens
    NDUFB5
    Mus musculus
    Ndufb5
    Rattus norvegicus
    Ndufb5

    External links

    FlyBase
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    Ensembl
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    Entrez Gene
    View on Entrez Gene database (46260)
    Homologues
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    UniProt
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    Internet
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