Caenorhabditis elegansGenAge entry for kat-1 (Caenorhabditis elegans)

Gene information (ID: 950)

Symbol
kat-1
Name
3-Ketoacyl-coA Thiolase
Organism
Caenorhabditis elegans (AnAge)

Potential relevance to longevity and/or ageing

Observations
Increased accumulation of the lipofuscin-like fluorescent aging pigment, shortened median lifespan (30% reduction compared to WT). Early behavioral decline, and other abnormalities characteristic of premature aging were observed.
% change in avg or median lifespan
Median lifespan is 53% lower.
Lifespan Effect
Decrease
Genetic Manipulation
Mutations
Longevity Category
Pro-Longevity
Primary reference

    Homologs in other organisms

    No homologs found

    External links

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    Entrez Gene
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