Caenorhabditis elegansGenAge entry for ire-1 (Caenorhabditis elegans)

Gene information (ID: 948)

Symbol
ire-1
Name
IRE1 kinase related
Organism
Caenorhabditis elegans (AnAge)

Potential relevance to longevity and/or ageing

Observations
Average lifespan decreased by 20% compared to wild type.
% change in avg or median lifespan
Average lifespan is 20% lower.
Lifespan Effect
Decrease
Genetic Manipulation
Mutation
Longevity Category
Pro-Longevity
Primary reference

    In other databases

    GenAge model organism genes
    • A homolog of this gene for Drosophila melanogaster is present as Ire1
    GenDR gene manipulations
    • A homolog of this gene for Drosophila melanogaster is present as Ire1
    • This gene is present as ire-1
    • A homolog of this gene for Saccharomyces cerevisiae is present as IRE1

    Homologs in other organisms

    Danio rerio
    ern2
    Drosophila melanogaster
    Ire1
    Homo sapiens
    ERN2
    Mus musculus
    Ern2
    Rattus norvegicus
    Ern2
    Saccharomyces cerevisiae
    IRE1
    Schizosaccharomyces pombe
    ppk4

    External links

    WormBase
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    Ensembl
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    Entrez Gene
    View on Entrez Gene database (174305)
    Homologues
    Search HomoloGene
    UniProt
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    Internet
    Search Google or Search Google Scholar