Caenorhabditis elegansGenAge entry for iftb-1 (Caenorhabditis elegans)

Gene information (ID: 384)

Symbol
iftb-1
Name
eIFTwoBeta (eIF2beta translation initiation factor)
Organism
Caenorhabditis elegans (AnAge)
Known functions and activities
A subunit of the general translation-initiation factor eIF2

Potential relevance to longevity and/or ageing

Observations
RNA interference in adulthood increased maximum lifespan by about 30%.
% change in max lifespan
Maximum lifespan is about 30% higher.
Lifespan Effect
Increase
Genetic Manipulation
RNA interference
Longevity Category
Anti-Longevity
Primary reference

    Homologs in other organisms

    Danio rerio
    eif2s2
    Drosophila melanogaster
    eIF-2beta
    Homo sapiens
    EIF2S2
    Mus musculus
    Gm9892
    Rattus norvegicus
    uncharacterized_D3ZB
    Saccharomyces cerevisiae
    SUI3
    Schizosaccharomyces pombe
    tif212

    External links

    WormBase
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    Ensembl
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    Entrez Gene
    View on Entrez Gene database (172584)
    Homologues
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    UniProt
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    Internet
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