Caenorhabditis elegansGenAge entry for hus-1 (Caenorhabditis elegans)

Gene information (ID: 356)

Symbol
hus-1
Name
human HUS1 related
Organism
Caenorhabditis elegans (AnAge)
Known functions and activities
DNA damage checkpoint protein

Potential relevance to longevity and/or ageing

Observations
RNA interference increased mean lifespan by 11%. In hus-1 mutants, RNA interference of cep-1 did not increase lifespan, suggesting both genes influence lifespan through the same pathway.
% change in avg or median lifespan
Average lifespan is 11% higher.
Lifespan Effect
Increase
Genetic Manipulation
RNA interference
Longevity Category
Anti-Longevity
Primary reference

    Homologs in other organisms

    Danio rerio
    zgc:162895
    Drosophila melanogaster
    Hus1-like
    Homo sapiens
    HUS1B
    Mus musculus
    Hus1b
    Rattus norvegicus
    Hus1b
    Schizosaccharomyces pombe
    hus1

    External links

    WormBase
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    Ensembl
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    Entrez Gene
    View on Entrez Gene database (171939)
    Homologues
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    UniProt
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    Internet
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