Caenorhabditis elegansGenAge entry for hlh-30 (Caenorhabditis elegans)

Gene information (ID: 2145)

Symbol
hlh-30
Name
Helix Loop Helix
Organism
Caenorhabditis elegans (AnAge)

Potential relevance to longevity and/or ageing

Observations
Worms overexpressing hlh-30 demonstrated a 15-20% increase in mean lifespan when compared to the wild type. This lifespan extension was linked to induction of autophagy.
% change in avg or median lifespan
Mean lifespan is 20% higher.
Lifespan Effect
Increase
Genetic Manipulation
Overexpression
Longevity Category
Pro-Longevity
Primary reference

    Homologs in other organisms

    Danio rerio
    tfec
    Homo sapiens
    TFEC
    Mus musculus
    Tfec
    Rattus norvegicus
    Tfec

    External links

    WormBase
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    Ensembl
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    Entrez Gene
    View on Entrez Gene database (177157)
    Homologues
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    UniProt
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    Internet
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