Caenorhabditis elegansGenAge entry for gpa-8 (Caenorhabditis elegans)

Gene information (ID: 317)

Symbol
gpa-8
Name
G Protein, Alpha subunit
Organism
Caenorhabditis elegans (AnAge)
Known functions and activities
G Protein, Alpha subunit

Potential relevance to longevity and/or ageing

Observations
Increase in mean lifespan by up to 20% in knockouts.
% change in avg or median lifespan
Average lifespan is up to 20% higher.
Lifespan Effect
Increase
Genetic Manipulation
Knockout
Longevity Category
Anti-Longevity
Primary reference
    Observations
    Decrease in mean lifespan of up to 10% when gpa-8 is overexpressed.
    % change in avg or median lifespan
    Average lifespan is 10% lower.
    Lifespan Effect
    Decrease
    Genetic Manipulation
    Overexpression
    Longevity Category
    Anti-Longevity
    Primary reference

      In other databases

      GenDR gene manipulations
      • A homolog of this gene for Schizosaccharomyces pombe is present as gpa2

      Homologs in other organisms

      Schizosaccharomyces pombe
      gpa2

      External links

      WormBase
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      Ensembl
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      Entrez Gene
      View on Entrez Gene database (179731)
      Homologues
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      UniProt
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      Internet
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