Caenorhabditis elegansGenAge entry for gpa-2 (Caenorhabditis elegans)

Gene information (ID: 313)

Symbol
gpa-2
Name
G Protein, Alpha subunit
Organism
Caenorhabditis elegans (AnAge)
Known functions and activities
G Protein, Alpha subunit

Potential relevance to longevity and/or ageing

Observations
Reduction in mean lifespan of 30% in gpa-2 knockouts.
% change in avg or median lifespan
Average lifespan is 30% lower.
Lifespan Effect
Decrease
Genetic Manipulation
Knockout
Longevity Category
Pro-Longevity
Primary reference
    Observations
    Mean lifespan extension of 12% when gpa-2 is overexpressed.
    % change in avg or median lifespan
    Average lifespan is 12% higher.
    Lifespan Effect
    Increase
    Genetic Manipulation
    Overexpression
    Longevity Category
    Pro-Longevity
    Primary reference

      Homologs in other organisms

      No homologs found

      External links

      WormBase
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      Ensembl
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      Entrez Gene
      View on Entrez Gene database (179219)
      Homologues
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      UniProt
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      Internet
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