Caenorhabditis elegansGenAge entry for glp-1 (Caenorhabditis elegans)

Gene information (ID: 308)

Symbol
glp-1
Name
abnormal Germ Line Proliferation
Organism
Caenorhabditis elegans (AnAge)
Known functions and activities
Receptor for a germ-line proliferation signal

Potential relevance to longevity and/or ageing

Observations
Mutations result in defects in germ-line proliferation and extension of lifespan by about 30%.
% change in avg or median lifespan
Lifespan is about 30% higher.
Lifespan Effect
Increase
Genetic Manipulation
Mutation
Longevity Category
Anti-Longevity
Primary reference
    Observations
    Post developmental RNAi resulted in a 33% mean lifespan extension.
    % change in avg or median lifespan
    Average lifespan is 33% higher.
    Lifespan Effect
    Increase
    Genetic Manipulation
    RNA interference
    Longevity Category
    Anti-Longevity
    Primary reference

      Homologs in other organisms

      Danio rerio
      LOC100535971

      External links

      WormBase
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      Ensembl
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      Entrez Gene
      View on Entrez Gene database (176286)
      Homologues
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      UniProt
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      Internet
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