Drosophila melanogasterGenAge entry for gig (Drosophila melanogaster)

Gene information (ID: 304)

Symbol
gig
Aliases
6975; C1; CG6975; Dmel\CG6975; dTsc2; dTSC2; gig|Tsc2; l(
Name
gigas
Organism
Drosophila melanogaster (AnAge)
Known functions and activities
Insulin/phosphoinositide 3-kinase (PI3K)/Akt pathway

Potential relevance to longevity and/or ageing

Observations
Overexpression of gig, also known as dTsc2, results in lifespan extension.
Lifespan Effect
Increase
Genetic Manipulation
Overexpression
Longevity Category
Pro-Longevity
Primary reference

    In other databases

    GenDR gene manipulations
    • This gene is present as gig
    LongevityMap
    • A homolog of this gene for Homo sapiens is present as TSC2

    Homologs in other organisms

    Danio rerio
    tsc2
    Homo sapiens
    TSC2
    Mus musculus
    Tsc2
    Rattus norvegicus
    Tsc2
    Schizosaccharomyces pombe
    tsc2

    External links

    FlyBase
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    Ensembl
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    Entrez Gene
    View on Entrez Gene database (40201)
    Homologues
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    UniProt
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    Internet
    Search Google or Search Google Scholar