Caenorhabditis elegansGenAge entry for ftt-2 (Caenorhabditis elegans)

Gene information (ID: 288)

Symbol
ftt-2
Name
Fourteen-Three-Three family
Organism
Caenorhabditis elegans (AnAge)

Potential relevance to longevity and/or ageing

Observations
Overexpression extended lifespan by about 30%. Life-extension was suppressed by daf-16 inactivation.
% change in avg or median lifespan
Lifespan is about 30% higher.
Lifespan Effect
Increase
Genetic Manipulation
Overexpression
Longevity Category
Pro-Longevity
Primary reference
    Observations
    Post developmental RNAi resulted in a 26% mean lifespan reduction in wild type though no significant changes in maximal lifespan were observed.
    % change in avg or median lifespan
    Average lifespan is 26% lower.
    Lifespan Effect
    Decrease
    Genetic Manipulation
    RNA interference
    Longevity Category
    Pro-Longevity
    Primary reference

      Homologs in other organisms

      No homologs found

      External links

      WormBase
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      Entrez Gene
      View on Entrez Gene database (181348)
      Homologues
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      UniProt
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      Internet
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