Caenorhabditis elegansGenAge entry for eif-3.K (Caenorhabditis elegans)

Gene information (ID: 2091)

Symbol
eif-3.K
Name
Eukaryotic translation initiation factor 3 subunit K
Organism
Caenorhabditis elegans (AnAge)

Potential relevance to longevity and/or ageing

Observations
In C. elegans mutants lacking eif-3.K, a nonessential eIF3 subunit, demonstrated a 40% increase in lifespan and enhanced resistance to endoplasmic reticulum stress.
% change in avg or median lifespan
Median lifespan is 40% higher.
Lifespan Effect
Increase
Genetic Manipulation
Mutation
Longevity Category
Anti-Longevity
Primary reference

    Homologs in other organisms

    Danio rerio
    eif3k
    Drosophila melanogaster
    CG10306
    Homo sapiens
    EIF3K
    Mus musculus
    Eif3k

    External links

    WormBase
    Search
    Ensembl
    Search
    Entrez Gene
    View on Entrez Gene database (179779)
    Homologues
    Search HomoloGene
    UniProt
    Search
    Internet
    Search Google or Search Google Scholar