Caenorhabditis elegansGenAge entry for egl-8 (Caenorhabditis elegans)

Gene information (ID: 920)

Symbol
egl-8
Name
EGg Laying defective
Organism
Caenorhabditis elegans (AnAge)

Potential relevance to longevity and/or ageing

Observations
Egl-8 mutants showed a 14% mean lifespan reduction (in the daf-16 background ) and a 83% mean lifespan extension (compared to wild type).
% change in avg or median lifespan
Median lifespan is 83% higher.
Lifespan Effect
Increase
Genetic Manipulation
Mutation
Longevity Category
Anti-Longevity
Primary reference
    Observations
    15% mean lifespan extension
    % change in avg or median lifespan
    Average lifespan is 15% higher.
    Lifespan Effect
    Increase
    Genetic Manipulation
    Mutation
    Longevity Category
    Anti-Longevity
    Primary reference

      Homologs in other organisms

      Danio rerio
      plcb3
      Drosophila melanogaster
      norpA
      Homo sapiens
      PLCB4
      Mus musculus
      Plcb4
      Rattus norvegicus
      Plcb4
      Schizosaccharomyces pombe
      plc1

      External links

      WormBase
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      Ensembl
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      Entrez Gene
      View on Entrez Gene database (178537)
      Homologues
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      UniProt
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      Internet
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