Caenorhabditis elegansGenAge entry for egl-45 (Caenorhabditis elegans)

Gene information (ID: 214)

Symbol
egl-45
Name
EGg Laying defective
Organism
Caenorhabditis elegans (AnAge)
Known functions and activities
Translation initiation factor (eIF) complex

Potential relevance to longevity and/or ageing

Observations
RNA interference in adulthood extended mean lifespan by 52%.
% change in avg or median lifespan
Average lifespan is 52% higher.
Lifespan Effect
Increase
Genetic Manipulation
RNA interference
Longevity Category
Anti-Longevity
Primary reference

    Homologs in other organisms

    Danio rerio
    eif3a
    Drosophila melanogaster
    eIF3-S10
    Homo sapiens
    EIF3A
    Mus musculus
    Eif3a
    Rattus norvegicus
    Eif3a
    Saccharomyces cerevisiae
    RPG1
    Schizosaccharomyces pombe
    tif32

    External links

    WormBase
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    Ensembl
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    Entrez Gene
    View on Entrez Gene database (176094)
    Homologues
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    UniProt
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    Internet
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