Drosophila melanogasterGenAge entry for dnc (Drosophila melanogaster)

Gene information (ID: 184)

Symbol
dnc
Aliases
CG10791; CG10792; CG10797; CG14267; CG14268; CG32498; Dm
Name
dunce
Organism
Drosophila melanogaster (AnAge)
Known functions and activities
cAMP phosphodiesterase

Potential relevance to longevity and/or ageing

Observations
cAMP phosphodiesterase-deficient dunce mutants had an extended maximum lifespan by about 70%.
% change in max lifespan
Maximal lifespan is 70% higher.
Lifespan Effect
Increase
Genetic Manipulation
Mutation
Longevity Category
Anti-Longevity
Primary reference

    Homologs in other organisms

    Caenorhabditis elegans
    pde-4
    Danio rerio
    pde4bb
    Mus musculus
    Pde4c
    Rattus norvegicus
    Pde4a

    External links

    FlyBase
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    Ensembl
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    Entrez Gene
    View on Entrez Gene database (31309)
    Homologues
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    UniProt
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    Internet
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