Caenorhabditis elegansGenAge entry for dlk-1 (Caenorhabditis elegans)

Gene information (ID: 181)

Symbol
dlk-1
Name
DAP (Death Associated Protein kinase) Like Kinase
Organism
Caenorhabditis elegans (AnAge)
Known functions and activities
Serine/threonine protein kinase

Potential relevance to longevity and/or ageing

Observations
Mutation reduced maximum lifespan by 30%.
% change in max lifespan
Maximum lifespan is 30% lower.
Lifespan Effect
Decrease
Genetic Manipulation
Mutation
Longevity Category
Pro-Longevity
Primary reference

    Homologs in other organisms

    Danio rerio
    si:ch211-45c16.2
    Homo sapiens
    MAP3K12
    Mus musculus
    Map3k12
    Rattus norvegicus
    Map3k13

    External links

    WormBase
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    Ensembl
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    Entrez Gene
    View on Entrez Gene database (173128)
    Homologues
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    UniProt
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    Internet
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