Caenorhabditis elegansGenAge entry for dlat-1 (Caenorhabditis elegans)

Gene information (ID: 2030)

Symbol
dlat-1
Name
Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex
Organism
Caenorhabditis elegans (AnAge)

Potential relevance to longevity and/or ageing

Observations
RNA interference of F23B12.5 results in an increased lifespan.
% change in avg or median lifespan
Mean lifespan is 9.9% higher.
Lifespan Effect
Increase
Genetic Manipulation
RNA interference
Longevity Category
Anti-Longevity
Primary reference

    In other databases

    GenAge model organism genes
    • A homolog of this gene for Saccharomyces cerevisiae is present as LAT1
    GenDR gene manipulations
    • A homolog of this gene for Saccharomyces cerevisiae is present as LAT1

    Homologs in other organisms

    Danio rerio
    dlat
    Drosophila melanogaster
    CG5261
    Homo sapiens
    DLAT
    Mus musculus
    Dlat
    Rattus norvegicus
    uncharacterized_M0RA
    Saccharomyces cerevisiae
    LAT1
    Schizosaccharomyces pombe
    lat1

    External links

    WormBase
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    Ensembl
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    Entrez Gene
    View on Entrez Gene database (179945)
    Homologues
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    UniProt
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    Internet
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