Drosophila melanogasterGenAge entry for dj-1beta (Drosophila melanogaster)

Gene information (ID: 179)

Symbol
dj-1beta
Aliases
CG1349; DJ-1; DJ-1b; DJ-1B; DJ-1beta; Dmel\CG1349
Name
dj-1beta
Organism
Drosophila melanogaster (AnAge)
Known functions and activities
Possibly involved in the pathogenesis of Parkinson disease

Potential relevance to longevity and/or ageing

Observations
Loss of function mutation shortened maximum lifespan by 40% and resulted in increased sensitivity to oxidative stress and motor impairments.
% change in max lifespan
Maximal lifespan is 40% lower.
Lifespan Effect
Decrease
Genetic Manipulation
Mutation
Longevity Category
Pro-Longevity
Primary reference

    In other databases

    LongevityMap
    • A homolog of this gene for Homo sapiens is present as PARK7

    Homologs in other organisms

    Danio rerio
    park7
    Homo sapiens
    PARK7
    Mus musculus
    Park7

    External links

    FlyBase
    Search
    Ensembl
    Search
    Entrez Gene
    View on Entrez Gene database (43652)
    Homologues
    Search HomoloGene
    UniProt
    Search
    Internet
    Search Google or Search Google Scholar