Caenorhabditis elegansGenAge entry for des-2 (Caenorhabditis elegans)

Gene information (ID: 175)

Symbol
des-2
Name
DEgeneration Suppressor
Organism
Caenorhabditis elegans (AnAge)
Known functions and activities
Alpha subunit of nicotinic acetylcholine receptor (nAChR)

Potential relevance to longevity and/or ageing

Observations
Mutations in both des(bs29) and des(bs30) increase lifespan by approximately 60%.
% change in avg or median lifespan
Lifespan is approximately 60% higher.
Lifespan Effect
Increase
Genetic Manipulation
Mutation
Longevity Category
Anti-Longevity
Primary reference

    Homologs in other organisms

    No homologs found

    External links

    WormBase
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    Ensembl
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    Entrez Gene
    View on Entrez Gene database (179574)
    Homologues
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    UniProt
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    Internet
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