Caenorhabditis elegansGenAge entry for dcr-1 (Caenorhabditis elegans)

Gene information (ID: 1858)

Symbol
dcr-1
Name
Endoribonuclease dcr-1
Organism
Caenorhabditis elegans (AnAge)

Potential relevance to longevity and/or ageing

Observations
Under normal growth conditions (20C) or modest heat stress (> 28C), dcr-1 mutants (Dicer-deficient) have decreased mean and maximum lifespan.
% change in max lifespan
Maximum lifespan is 20% lower.
Lifespan Effect
Decrease
Genetic Manipulation
Mutation
Longevity Category
Pro-Longevity
Primary reference

    Homologs in other organisms

    Danio rerio
    dicer1
    Drosophila melanogaster
    Dcr-1
    Homo sapiens
    DICER1
    Mus musculus
    Dicer1
    Rattus norvegicus
    Dicer1
    Schizosaccharomyces pombe
    dcr1

    External links

    WormBase
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    Ensembl
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    Entrez Gene
    View on Entrez Gene database (176138)
    Homologues
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    UniProt
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    Internet
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