Caenorhabditis elegansGenAge entry for daf-14 (Caenorhabditis elegans)

Gene information (ID: 158)

Symbol
daf-14
Name
abnormal DAuer Formation
Organism
Caenorhabditis elegans (AnAge)
Known functions and activities
Possibly a transducer of the DAF-7/TGF-beta-mediated signal that promotes reproductive growth and ne

Potential relevance to longevity and/or ageing

Observations
Mutation in adults increased mean lifespan by up to 44% and maximum lifespan by 50%.
% change in max lifespan
Maximum lifespan is 50% higher.
% change in avg or median lifespan
Average lifespan is up to 44% higher.
Lifespan Effect
Increase
Genetic Manipulation
Mutation
Longevity Category
Anti-Longevity
Primary reference

    Homologs in other organisms

    No homologs found

    External links

    WormBase
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    Ensembl
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    Entrez Gene
    View on Entrez Gene database (177908)
    Homologues
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    UniProt
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    Internet
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