Caenorhabditis elegansGenAge entry for daf-1 (Caenorhabditis elegans)

Gene information (ID: 156)

Symbol
daf-1
Name
abnormal DAuer Formation
Organism
Caenorhabditis elegans (AnAge)
Known functions and activities
Encodes a TGF-beta type I receptor homolog

Potential relevance to longevity and/or ageing

Observations
Mutation in adults increased mean lifespan by up to 46% and maximum lifespan by 50%.
% change in max lifespan
Maximum lifespan is 50% higher.
% change in avg or median lifespan
Average lifespan is 46% higher.
Lifespan Effect
Increase
Genetic Manipulation
Mutation
Longevity Category
Anti-Longevity
Primary reference

    Homologs in other organisms

    Danio rerio
    CABZ01079442.1
    Homo sapiens
    ACVRL1
    Mus musculus
    Acvrl1
    Rattus norvegicus
    Acvrl1

    External links

    WormBase
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    Ensembl
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    Entrez Gene
    View on Entrez Gene database (176829)
    Homologues
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    UniProt
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    Internet
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