Caenorhabditis elegansGenAge entry for cth-1 (Caenorhabditis elegans)

Gene information (ID: 1971)

Symbol
cth-1
Name
CystaTHionine gamma lyase
Organism
Caenorhabditis elegans (AnAge)

Potential relevance to longevity and/or ageing

Observations
RNA interference of CTH-1 in worms results in median lifespan reduction (~15%), however maximal lifespan is not significantly different than that of controls.
% change in avg or median lifespan
Median lifespan is 15% lower.
Lifespan Effect
Decrease
Genetic Manipulation
RNA interference
Longevity Category
Pro-Longevity
Primary reference

    Homologs in other organisms

    Danio rerio
    cthl
    Drosophila melanogaster
    Eip55E
    Homo sapiens
    CTH
    Mus musculus
    Cth
    Rattus norvegicus
    Cth
    Saccharomyces cerevisiae
    CYS3
    Schizosaccharomyces pombe
    SPBC428.11

    External links

    WormBase
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    Ensembl
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    Entrez Gene
    View on Entrez Gene database (180079)
    Homologues
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    UniProt
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    Internet
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