Caenorhabditis elegansGenAge entry for cku-70 (Caenorhabditis elegans)

Gene information (ID: 129)

Symbol
cku-70
Name
Caenorhabditis KU
Organism
Caenorhabditis elegans (AnAge)
Known functions and activities
DNA-binding subunit of a DNA-dependent protein kinase

Potential relevance to longevity and/or ageing

Observations
RNA interference of cku-70 further increases the lifespan of daf-2 mutants. Lifespan of daf-16 mutants was slightly decreased.
Lifespan Effect
Increase
Genetic Manipulation
RNA interference
Longevity Category
Anti-Longevity
Primary reference

    In other databases

    GenAge model organism genes
    • A homolog of this gene for Mus musculus is present as Xrcc6
    GenAge human genes
    • A homolog of this gene for Homo sapiens is present as XRCC6
    LongevityMap
    • A homolog of this gene for Homo sapiens is present as XRCC6

    Homologs in other organisms

    Danio rerio
    xrcc6
    Drosophila melanogaster
    Irbp
    Homo sapiens
    XRCC6
    Mus musculus
    Xrcc6
    Rattus norvegicus
    Xrcc6
    Schizosaccharomyces pombe
    pku70

    External links

    WormBase
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    Ensembl
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    Entrez Gene
    View on Entrez Gene database (176546)
    Homologues
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    UniProt
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    Internet
    Search Google or Search Google Scholar