Caenorhabditis elegansGenAge entry for chk-1 (Caenorhabditis elegans)

Gene information (ID: 125)

Symbol
chk-1
Name
CHeckpoint Kinase
Organism
Caenorhabditis elegans (AnAge)
Known functions and activities
chk-1 encodes a CHK1-like serine threonin protein kinase that affects fertility

Potential relevance to longevity and/or ageing

Observations
RNA interference increased lifespan by 15 to 25%.
% change in avg or median lifespan
Lifespan is 15-25% higher.
Lifespan Effect
Increase
Genetic Manipulation
RNA interference
Longevity Category
Anti-Longevity
Primary reference

    In other databases

    CellAge
    • A homolog of this gene for Homo sapiens is present as CHEK1

    Homologs in other organisms

    Danio rerio
    chek1
    Drosophila melanogaster
    grp
    Homo sapiens
    CHEK1
    Mus musculus
    Chek1
    Rattus norvegicus
    Chek1

    External links

    WormBase
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    Ensembl
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    Entrez Gene
    View on Entrez Gene database (3565921)
    Homologues
    Search HomoloGene
    UniProt
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    Internet
    Search Google or Search Google Scholar