Drosophila melanogasterGenAge entry for chico (Drosophila melanogaster)

Gene information (ID: 124)

Symbol
chico
Aliases
anon-WO0078940.1; anon-WO0078940.4; BcDNA.GH11263; Bc
Name
Insulin receptor substrate-1
Organism
Drosophila melanogaster (AnAge)
Known functions and activities
Insulin receptor substrate

Potential relevance to longevity and/or ageing

Observations
Lifespan extension of 48% in homozygotes and 36% in heterozygotes.
% change in avg or median lifespan
Lifespan is up to 48% higher.
Lifespan Effect
Increase
Genetic Manipulation
Knockout
Longevity Category
Anti-Longevity
Primary reference

    In other databases

    GenDR gene manipulations
    • This gene is present as chico

    Homologs in other organisms

    No homologs found

    External links

    FlyBase
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    Ensembl
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    Entrez Gene
    View on Entrez Gene database (64880)
    Homologues
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    UniProt
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    Internet
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