Caenorhabditis elegansGenAge entry for che-3 (Caenorhabditis elegans)

Gene information (ID: 121)

Symbol
che-3
Name
abnormal CHEmotaxis
Organism
Caenorhabditis elegans (AnAge)
Known functions and activities
Required for proper structure of sensory cilia

Potential relevance to longevity and/or ageing

Observations
Loss-of-function extends lifespan by 50-100%, but life-extension is suppressed by daf-16.
% change in avg or median lifespan
Lifespan is 50-100% higher.
Lifespan Effect
Increase
Genetic Manipulation
Mutation
Longevity Category
Anti-Longevity
Primary reference

    Homologs in other organisms

    Drosophila melanogaster
    btv
    Homo sapiens
    DYNC2H1
    Mus musculus
    Dync2h1
    Rattus norvegicus
    Dync2h1

    External links

    WormBase
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    Ensembl
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    Entrez Gene
    View on Entrez Gene database (172593)
    Homologues
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    UniProt
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    Internet
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