Drosophila melanogasterGenAge entry for cert (Drosophila melanogaster)

Gene information (ID: 117)

Symbol
cert
Aliases
BcDNA:GH07688; CERT; CG7207; dcert; Dcert; Dmel\CG7207
Name
ceramide transfer protein
Organism
Drosophila melanogaster (AnAge)
Known functions and activities
Ceramide transfer protein

Potential relevance to longevity and/or ageing

Observations
Mutant flies exhibited a shortened lifespan accompanied by enhanced oxidative damage to cellular proteins and metabolic compromise, such as increasing glucose levels, reminiscent of premature ageing.
Lifespan Effect
Decrease
Genetic Manipulation
Mutation
Longevity Category
Pro-Longevity
Primary reference

    Homologs in other organisms

    Caenorhabditis elegans
    CELE_F25H2.6
    Danio rerio
    uncharacterized_F1QT
    Homo sapiens
    COL4A3BP
    Mus musculus
    Col4a3bp
    Rattus norvegicus
    Col4a3bp

    External links

    FlyBase
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    Ensembl
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    Entrez Gene
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    Homologues
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    UniProt
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    Internet
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