Caenorhabditis elegansGenAge entry for cdc-48.1 (Caenorhabditis elegans)

Gene information (ID: 1759)

Symbol
cdc-48.1
Name
Protein CDC-48.1
Organism
Caenorhabditis elegans (AnAge)

Potential relevance to longevity and/or ageing

Observations
In contrast to single deletions, worms deficient for both cdc-48.1 (p97) and atx-3 have an extended lifespan, modulated through the insulin/IGF-1 signalling pathway.
% change in avg or median lifespan
Lifespan is up to 50% higher.
Lifespan Effect
Increase
Genetic Manipulation
Mutation
Longevity Category
Anti-Longevity
Primary reference

    In other databases

    GenAge human genes
    • A homolog of this gene for Homo sapiens is present as VCP

    Homologs in other organisms

    Danio rerio
    zgc:136908
    Homo sapiens
    VCP
    Mus musculus
    Vcp
    Rattus norvegicus
    Vcp

    External links

    WormBase
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    Ensembl
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    Entrez Gene
    View on Entrez Gene database (174624)
    Homologues
    Search HomoloGene
    UniProt
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    Internet
    Search Google or Search Google Scholar