Caenorhabditis elegansGenAge entry for cco-2 (Caenorhabditis elegans)

Gene information (ID: 96)

Symbol
cco-2
Name
Cytochrome C Oxidase
Organism
Caenorhabditis elegans (AnAge)
Known functions and activities
Cytochrome c oxidase, subunit Va/COX6

Potential relevance to longevity and/or ageing

Observations
RNA interference results in a 53-57% increase in mean lifespan.
% change in avg or median lifespan
Average lifespan is 53-57% higher.
Lifespan Effect
Increase
Genetic Manipulation
RNA interference
Longevity Category
Anti-Longevity
Primary reference
    Observations
    RNAi resulted in a 60% mean lifespan extension.
    % change in avg or median lifespan
    Average lifespan is 60% higher.
    Lifespan Effect
    Increase
    Genetic Manipulation
    RNA interference
    Longevity Category
    Anti-Longevity
    Primary reference

      Homologs in other organisms

      Danio rerio
      cox5aa
      Drosophila melanogaster
      CoVa
      Homo sapiens
      COX5A
      Mus musculus
      Cox5a
      Rattus norvegicus
      Cox5a
      Schizosaccharomyces pombe
      cox6

      External links

      WormBase
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      Ensembl
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      Entrez Gene
      View on Entrez Gene database (176707)
      Homologues
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      UniProt
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      Internet
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