Caenorhabditis elegansGenAge entry for cchl-1 (Caenorhabditis elegans)

Gene information (ID: 94)

Symbol
cchl-1
Name
Cytochrome C Heme-Lyase
Organism
Caenorhabditis elegans (AnAge)
Known functions and activities
Holocytochrome c synthase/heme-lyase

Potential relevance to longevity and/or ageing

Observations
RNA interference results in about 50% lifespan extension.
% change in avg or median lifespan
Lifespan is about 50% higher.
Lifespan Effect
Increase
Genetic Manipulation
RNA interference
Longevity Category
Anti-Longevity
Primary reference
    Observations
    RNAi resulted in a 19-36% mean lifespan extension.
    % change in avg or median lifespan
    Average lifespan is 19-36% higher.
    Lifespan Effect
    Increase
    Genetic Manipulation
    RNA interference
    Longevity Category
    Anti-Longevity
    Primary reference

      In other databases

      GenAge model organism genes
      • A homolog of this gene for Saccharomyces cerevisiae is present as CYC3

      Homologs in other organisms

      Danio rerio
      hccsa
      Drosophila melanogaster
      Cchl
      Homo sapiens
      HCCS
      Mus musculus
      Hccs
      Rattus norvegicus
      Hccs
      Saccharomyces cerevisiae
      CYC3
      Schizosaccharomyces pombe
      SPAC24C9.02c

      External links

      WormBase
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      Ensembl
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      Entrez Gene
      View on Entrez Gene database (174713)
      Homologues
      Search HomoloGene
      UniProt
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      Internet
      Search Google or Search Google Scholar