Drosophila melanogasterGenAge entry for bchs (Drosophila melanogaster)

Gene information (ID: 41)

Symbol
bchs
Aliases
alfy; BcDNA:SD12984; bchd; Bchs; Beach1; CG14001; CG9011
Name
blue cheese
Organism
Drosophila melanogaster (AnAge)
Known functions and activities
Scaffolding protein

Potential relevance to longevity and/or ageing

Observations
Mean lifespan is decreased 40-45% in bchs mutant adults. No pronounced developmental defects were observed and young adults have normal behaviors, indicating that the bchs gene is essential for normal adult survival and longevity.
% change in avg or median lifespan
Average lifespan is 40-45% lower.
Lifespan Effect
Decrease
Genetic Manipulation
Mutation
Longevity Category
Pro-Longevity
Primary reference
    Observations
    Mutants showed a 13% reduction in maximum lifespan.
    % change in max lifespan
    Maximum lifespan is 13% lower.
    Lifespan Effect
    Decrease
    Genetic Manipulation
    Mutations
    Longevity Category
    Pro-Longevity
    Primary reference
      Observations
      Mutants showed a 40% reduction in maximum lifespan.
      % change in max lifespan
      Maximum lifespan is 40% lower.
      Lifespan Effect
      Decrease
      Genetic Manipulation
      Mutation
      Longevity Category
      Pro-Longevity
      Primary reference

        Homologs in other organisms

        Caenorhabditis elegans
        C26H9A.2
        Danio rerio
        si:ch211-259k10.1
        Homo sapiens
        WDFY3
        Mus musculus
        Wdfy3
        Rattus norvegicus
        Wdfy3
        Schizosaccharomyces pombe
        lvs1

        External links

        FlyBase
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        Ensembl
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        Entrez Gene
        View on Entrez Gene database (33819)
        Homologues
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        UniProt
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        Internet
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