Caenorhabditis elegansGenAge entry for bcat-1 (Caenorhabditis elegans)

Gene information (ID: 2112)

Symbol
bcat-1
Name
Branched-chain-amino-acid aminotransferase, cytosolic
Organism
Caenorhabditis elegans (AnAge)

Potential relevance to longevity and/or ageing

Observations
Downregulation of bcat-1 in worms increased mean lifespan by 25% and maximum lifespan by 19%. In addition to extending lifespan bcat-1 downregulation also increased health span.
% change in max lifespan
Maximum lifespan is 19% higher.
% change in avg or median lifespan
Mean lifespan is 25% higher.
Lifespan Effect
Increase
Genetic Manipulation
RNA interference
Longevity Category
Anti-Longevity
Primary reference

    Homologs in other organisms

    Danio rerio
    bcat1
    Drosophila melanogaster
    CG1673
    Homo sapiens
    BCAT2
    Mus musculus
    Bcat2
    Rattus norvegicus
    Bcat2

    External links

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    Entrez Gene
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    Homologues
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    UniProt
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    Internet
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