Caenorhabditis elegansGenAge entry for atx-3 (Caenorhabditis elegans)

Gene information (ID: 1758)

Symbol
atx-3
Name
Protein ATX-3
Organism
Caenorhabditis elegans (AnAge)

Potential relevance to longevity and/or ageing

Observations
In contrast to single deletions, worms deficient for both cdc-48.1 (p97) and atx-3 have an extended lifespan, modulated through the insulin/IGF-1 signalling pathway.
% change in avg or median lifespan
Lifespan is up to 50% higher.
Lifespan Effect
Increase
Genetic Manipulation
Mutation
Longevity Category
Anti-Longevity
Primary reference

    Homologs in other organisms

    Danio rerio
    uncharacterized_F1QQ
    Homo sapiens
    ATXN3L
    Mus musculus
    Atxn3
    Rattus norvegicus
    Atxn3

    External links

    WormBase
    Search
    Ensembl
    Search
    Entrez Gene
    View on Entrez Gene database (180049)
    Homologues
    Search HomoloGene
    UniProt
    Search
    Internet
    Search Google or Search Google Scholar