Caenorhabditis elegansGenAge entry for atg-18 (Caenorhabditis elegans)

Gene information (ID: 893)

Symbol
atg-18
Name
AuTophaGy (yeast Atg homolog)
Organism
Caenorhabditis elegans (AnAge)

Potential relevance to longevity and/or ageing

Observations
20% reduction in mean LS
% change in avg or median lifespan
Average lifespan is 20% lower.
Lifespan Effect
Decrease
Genetic Manipulation
RNA interference
Longevity Category
Pro-Longevity
Primary reference
    Observations
    47% maximal lifespan reduction by postdevelopmental RNAi while RNAi fron the beginning of life had no effect.
    % change in max lifespan
    Maximum lifespan is 47% lower.
    Lifespan Effect
    Decrease
    Genetic Manipulation
    RNA interference
    Longevity Category
    Anti-Longevity
    Primary reference

      In other databases

      GenAge model organism genes
      • A homolog of this gene for Saccharomyces cerevisiae is present as ATG18

      Homologs in other organisms

      Danio rerio
      LOC100332293
      Drosophila melanogaster
      CG8678
      Homo sapiens
      WIPI1
      Mus musculus
      Wipi1
      Rattus norvegicus
      Wipi1
      Saccharomyces cerevisiae
      ATG18
      Schizosaccharomyces pombe
      atg18

      External links

      WormBase
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      Ensembl
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      Entrez Gene
      View on Entrez Gene database (179246)
      Homologues
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      UniProt
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      Internet
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