Caenorhabditis elegansGenAge entry for atad-3 (Caenorhabditis elegans)

Gene information (ID: 2012)

Symbol
atad-3
Name
ATPase family AAA domain-containing protein 3
Organism
Caenorhabditis elegans (AnAge)

Potential relevance to longevity and/or ageing

Observations
RNA interference of mics-1 results in mutants with enhanced longevity when compated to HT115 wild-type controls (mean lifespan is 29% higher). Mutants are however highly sensitive to stress, displaying significantly higher levels of reactive oxygen species.
% change in avg or median lifespan
Mean lifespan is 29% higher.
Lifespan Effect
Increase
Genetic Manipulation
RNA interference
Longevity Category
Anti-Longevity
Primary reference

    Homologs in other organisms

    Drosophila melanogaster
    bor
    Homo sapiens
    ATAD3A
    Mus musculus
    Atad3
    Rattus norvegicus
    Atad3

    External links

    WormBase
    Search
    Ensembl
    Search
    Entrez Gene
    View on Entrez Gene database (174590)
    Homologues
    Search HomoloGene
    UniProt
    Search
    Internet
    Search Google or Search Google Scholar