Caenorhabditis elegansGenAge entry for argk-1 (Caenorhabditis elegans)

Gene information (ID: 2107)

Symbol
argk-1
Name
ARGinine Kinase
Organism
Caenorhabditis elegans (AnAge)

Potential relevance to longevity and/or ageing

Observations
Worms overexpressing argk-1 lived up to 25% longer at 25 and 20 degrees Celsius when compared tp the wild type. Argk-1 was found to be required for the reduced body size and increased stress resistance observed in rsks-1/S6K mutants.
% change in avg or median lifespan
Mean lifespan is 25% higher.
Lifespan Effect
Increase
Genetic Manipulation
Overexpression
Longevity Category
Pro-Longevity
Primary reference

    Homologs in other organisms

    Danio rerio
    zgc:56085
    Drosophila melanogaster
    CG5144
    Homo sapiens
    CKMT2
    Mus musculus
    Ckmt2
    Rattus norvegicus
    Ckmt2

    External links

    WormBase
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    Ensembl
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    Entrez Gene
    View on Entrez Gene database (180080)
    Homologues
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    UniProt
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    Internet
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