Caenorhabditis elegansGenAge entry for apy-1 (Caenorhabditis elegans)

Gene information (ID: 889)

Symbol
apy-1
Name
APYrase
Organism
Caenorhabditis elegans (AnAge)

Potential relevance to longevity and/or ageing

Observations
Some of the apy-1 (RNAi) phenotypes are suggestive of premature aging, since these animals also showed accumulation of lipofuscin and reduced maximal lifespan (by 30%)
% change in max lifespan
Maximum lifespan is 30% lower.
Lifespan Effect
Decrease
Genetic Manipulation
RNA interference post development
Longevity Category
Pro-Longevity
Primary reference

    Homologs in other organisms

    Danio rerio
    LOC100537965
    Drosophila melanogaster
    CG5276
    Homo sapiens
    CANT1
    Mus musculus
    Cant1
    Rattus norvegicus
    Cant1

    External links

    WormBase
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    Ensembl
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    Entrez Gene
    View on Entrez Gene database (181019)
    Homologues
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    UniProt
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    Internet
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