- Symbol
- aco-2
- Name
- ACOnitase
- Organism
- Caenorhabditis elegans (AnAge)
- Known functions and activities
- Required for embryonic viability, fertility, locomotion, and vulval morphogenesis
- Observations
- RNA interference of aco-2 results in an increased lifespan.
- % change in avg or median lifespan
- Mean lifespan is 20.5% higher.
- Lifespan Effect
- Increase
- Genetic Manipulation
- RNA interference
- Longevity Category
- Anti-Longevity
- Primary reference
-
- Observations
- RNA interference leads to lifespan extension.
- Lifespan Effect
- Increase
- Genetic Manipulation
- RNA interference
- Longevity Category
- Anti-Longevity
- Primary reference
-
- Observations
- 30% mean lifespan extension in daf2 background; no lifespan measurement in wt background
- Lifespan Effect
- Increase
- Genetic Manipulation
- RNA interference
- Longevity Category
- Anti-Longevity
- Primary reference
-
- Danio rerio
- aco2
- Drosophila melanogaster
- CG4706
- Drosophila melanogaster
- Acon
- Homo sapiens
- ACO2
- Mus musculus
- Aco2
- Rattus norvegicus
- Aco2
- Saccharomyces cerevisiae
- ACO1
- Schizosaccharomyces pombe
- SPAC24C9.06c
- WormBase
- Search
- Ensembl
- Search
- Entrez Gene
- View on Entrez Gene database (176121)
- Homologues
- Search HomoloGene
- UniProt
- Search
- Internet
- Search Google or Search Google Scholar
GenAge entry for aco-2 (Caenorhabditis elegans)