Drosophila melanogasterGenAge entry for Trx-2 (Drosophila melanogaster)

Gene information (ID: 685)

Symbol
Trx-2
Aliases
31884; anon-WO0118547.188; CG31884; CG3864; DmelTrx-2;
Name
thioredoxin-2
Organism
Drosophila melanogaster (AnAge)
Known functions and activities
Thioredoxin

Potential relevance to longevity and/or ageing

Observations
Mutants have a 25% reduction in maximum lifespan and exhibited lower tolerance to oxidative stress while animals carrying multiple copies of Trx-2 exhibited higher tolerance.
% change in max lifespan
Maximum lifespan is 25% lower.
Lifespan Effect
Decrease
Genetic Manipulation
Mutation
Longevity Category
Pro-Longevity
Primary reference

    Homologs in other organisms

    Caenorhabditis elegans
    trx-4
    Schizosaccharomyces pombe
    trx1

    External links

    FlyBase
    Search
    Ensembl
    Search
    Entrez Gene
    View on Entrez Gene database (34281)
    Homologues
    Search HomoloGene
    UniProt
    Search
    Internet
    Search Google or Search Google Scholar