Mus musculusGenAge entry for Trp73 (Mus musculus)

Gene information (ID: 1801)

Symbol
Trp73
Aliases
p73; Tp73
Name
transformation related protein 73
Organism
Mus musculus (AnAge)

Potential relevance to longevity and/or ageing

Observations
Knockout mice exhibit features resembling accelerated ageing, including reduced survival, kyphosis and increased levels of oxidized proteins.
% change in avg or median lifespan
Average lifespan is 31% lower.
Lifespan Effect
Decrease
Genetic Manipulation
Knockout
Longevity Category
Pro-Longevity
Primary reference

    In other databases

    GenAge human genes
    • A homolog of this gene for Homo sapiens is present as TP73

    Homologs in other organisms

    Danio rerio
    tp73
    Homo sapiens
    TP73
    Rattus norvegicus
    Tp73

    External links

    Mouse Genome Informatics
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    Ensembl
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    Entrez Gene
    View on Entrez Gene database (22062)
    Homologues
    Search HomoloGene
    UniProt
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    Internet
    Search Google or Search Google Scholar