Mus musculusGenAge entry for Top3b (Mus musculus)

Gene information (ID: 677)

Symbol
Top3b
Name
Topoisomerase (DNA) III beta
Organism
Mus musculus (AnAge)
Known functions and activities
Involved in the supercoiling of the DNA.

Potential relevance to longevity and/or ageing

Observations
Deletion results in a normal development but a shorter lifespan accompanied by lesions in multiple organs.
Lifespan Effect
Decrease
Genetic Manipulation
Deletion
Longevity Category
Pro-Longevity
Primary reference

    In other databases

    GenAge human genes
    • A homolog of this gene for Homo sapiens is present as TOP3B

    Homologs in other organisms

    Caenorhabditis elegans
    CELE_Y48C3A.14
    Danio rerio
    top3b
    Drosophila melanogaster
    Top3beta
    Homo sapiens
    TOP3B
    Rattus norvegicus
    Top3b

    External links

    Mouse Genome Informatics
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    Ensembl
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    Entrez Gene
    View on Entrez Gene database (21976)
    Homologues
    Search HomoloGene
    UniProt
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    Internet
    Search Google or Search Google Scholar