Saccharomyces cerevisiaeGenAge entry for TOM1 (Saccharomyces cerevisiae)

Gene information (ID: 1646)

Symbol
TOM1
Name
Temperature dependent Organization in Mitotic nucleus
Organism
Saccharomyces cerevisiae (AnAge)

Potential relevance to longevity and/or ageing

Observations
Tom1 mutants exhibit increased replicative lifespan.
% change in avg or median lifespan
Mean replicative lifespan is 30% higher.
Lifespan Effect
Increase
Genetic Manipulation
Deletion
Longevity Category
Anti-Longevity
Primary reference
    Observations
    Replicative lifespan increased by 10%-20% in the alpha and a strains
    % change in avg or median lifespan
    Replicative lifespan is 10-20% higher.
    Lifespan Effect
    Increase
    Genetic Manipulation
    Deletion
    Longevity Category
    Anti-Longevity
    Primary reference

      Homologs in other organisms

      Caenorhabditis elegans
      eel-1
      Danio rerio
      huwe1
      Homo sapiens
      HUWE1
      Mus musculus
      Huwe1
      Schizosaccharomyces pombe
      ptr1

      External links

      Saccharomyces Genome Database
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      Ensembl
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      Entrez Gene
      View on Entrez Gene database (852068)
      Homologues
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      UniProt
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      Internet
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